Limited human research
Melanotan II
Melanotan II is a cyclic lactam peptide and a non-selective agonist at melanocortin receptors, including MC1, MC3, MC4, and MC5. It is not an approved drug. The catalogue includes it as the MT2 PRO 20 mg research pen.
Research summary only. Not medical advice, not a protocol, and not for human or veterinary consumption.
- Also called
- MT-II, MT2
- CAS
- 121062-08-6
- Sequence or structure
- Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
- Evidence
- Limited human research
Mechanism
It was designed at the University of Arizona as a more stable melanocortin agonist than α-MSH. MC1R activity is tied to pigmentation in experimental systems. MC3R and MC4R activity is tied to other central effects. Non-selectivity is the point, and it is also the problem.
Evidence
Early research administrations were published. What followed in the unlicensed market is a case literature, not a development program that ended in approval. There is no licensed melanotan II product to distinguish this profile from, because there is no licence.
Limitations
Case reports associated with unlicensed use describe nausea, raised blood pressure, prolonged erections, and changing moles. Those reports are a reason for caution, not a how-to, and this site does not explain how the peptide has been taken. The pen is a research record, not a medicine. Not for human use.
